Prof. Dr. med. Veit Hornung



Prof. Dr. Veit Hornung

Institute for Clinical Chemistry and Clinical Pharmacology

Medical FacultyUniversity of Bonn

Sigmund-Freud-Str. 25, 53105 Bonn

Phone: 0228-287-51200,  Fax: 0228-287-51201



Honors & Awards (Selection)                     

2002                     Study Scholarship of the Munich-Harvard-Alliance

2006                     Graduate-Scholarship of the Novartis-Foundation for Therapeutical Research

2003                     Johann Peter Frank Award (German Society of Public Health Officers) 

2007                     Heinz Maier Leibnitz Prize of the German Research Foundation

2010                     Paul-Martini-Prize of the Paul-Martini-Foundation


Selected Publications

  • Hornung, V., Guenthner-Biller, M., Bourquin, C., Ablasser, A., Schlee, M., Uematsu, S., Noronha, A., Manoharan, M.,Akira, S., de Fougerolles, A., Endres, S. and Hartmann, G. (2005) Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7, Nat Med. 11: 263-70.
  • Hornung, V., Ellegast, J., Kim, S., Brzozka, K., Jung, A., Kato, H., Poeck, H., Akira, S., Conzelmann, K. K., Schlee, M.,Endres, S. and Hartmann, G. (2006) 5'-Triphosphate RNA is the ligand for RIG-I, Science. 314: 994-7.
  • Hornung, V.*, Bauernfeind, F.*, Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A. and Latz, E. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization, NatImmunol. 9: 847-56.
  • Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E. and Fitzgerald, K. A. (2009) AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC, Nature. 458: 514-8.
  • Ablasser, A., Bauernfeind, F., Hartmann, G., Latz, E., Fitzgerald, K. A.* and Hornung, V.* (2009) RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate, Nat Immunol. 10: 1065-72.* equal contributions